Presentation:
Clobetasol Propionate  Cream: Each gram cream contains Clobetasol Propionate BP 0.5 mg (0.05% w/w).
Clobetasol Propionate Ointment: Each gram ointment contains Clobetasol Propionate BP 0.5 mg (0.05% w/w).
Clobetasol Propionate NN Cream: Each gram cream contains Clobetasol Propionate BP 0.5 mg (0.05% w/w), Neomycin Sulphate BP 5 mg (0.5% w/w)) and Nystatin BP 1,00,00,000 IU.
Clobetasol Propionate Scalp Application: Each gram lotion contains Clobetasol Propionate BP 0.50 mg.

Indications and Uses:
Eczema unresponsive to weak steroid cream or ointment
Other inflammatory skin disorders resistant to treatment with weaker steroid creams or ointment
Psoriasis
Any inflammatory skin disorders where secondary bacterial or candidal infection is present, suspected or likely to occur.

Dosage and Administration:
Clobetasol Propionate Cream & Ointment
Adults and children over 1 years:
Apply sparingly to cover the affected area, and gently rub into the skin. Frequency of application is 2 to 3 times daily according to the severity of the condition. The total dose applied should not exceed 50g weekly.
Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient's condition being reviewed
Repeated short courses of Clobetasol may be used to control exacerbations
Children below 1 year:
Under 1 year this preparation is not recommended

Clobetasol Propionate NN Cream:
Adults and children over 1 year:
Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations therapy should be discontinued when control is achieved
In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effect of preparaton can be enhanced, if necessary, by occluding the treatment area with polythene
Treatment should not be continued for more than 7 days without medical supervision. If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient's condition being reviewed
Repeated short courses of Nyclobate NN may be used to control exacerbations
Nyclobate Scalp Application:
Apply sparingly to the scalp two times daily night and morning until improvement occurs.
As with other highly-active topical steroid preparations, therapy should be discontinued when control is achieved.
Repeated short courses may be used to control exacerbations.
Elderly:
This preparation is suitable for use in the elderly. Caution should be exercised in cases where a decrease in renal function exists and significant systemic absorption of Neomycin Sulphate may occur.
Children:
Under 1 year this preparation is not recommended.

Side-effects:
Generally this preparation is well tolerated. However, few side effects after prolonged and intensive treatment may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels, particularly when occlusive dressings are used, or when skin folds are involved.