Welcome Guest | Login | Registration


Azithromycin

Presentation
Azithromycin Tablet: Each tablet contains Azithromycin Dihydrate USP 524.03 mg equivalent to Azithromycin 500 mg.
Azithromycin 250 Tablet: Each tablet contains Azithromycin Dihydrate USP 262.015 mg equivalent to Azithromycin 250 mg.
Azithromycin Dry Suspension: After reconstitution, each 5 ml suspension contains Azithromycin Dihydrate USP 209.65 mg equivalent to Azithromycin 200 mg.
Azithromycin 35 ml Suspension: After reconstitution, each 5 ml suspension contains Azithromycin Dihydrate USP 209.65 mg equivalent to Azithromycin 200 mg.
Azithromycin injection: Each vial contains lyophilized powder of Azithromycin Dihydrate USP equivalent to Azithromycin 500 mg, after reconstitution according to direction each ml contains Azithromycin Dihydrate USP equivalent to Azithromycin 100 mg.

Description
Azithromycin is an azalide antibiotic, a subclass of macrolide antibiotic. It acts by binding to the 50s ribosomal subunit of susceptible microorganisms and thus interfering with microbial protein synthesis. Azithromycin has been shown to be active against most strains in the following microorganisms, both In vitro and in clinical infections:
Gram-positive microorganisms: Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes.
Gram-negative microorganisms: Haemophilus ducreyi, Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, Escherichia coli.
Other microorganisms: Chlamydia pneumoniae, Chlamydia trachomatis, Mycoplasma pneumoniae, Bacteroides fragilis, Legionella pneumophila, oxoplasma gondii.

Indications and Uses
Azithromycin is indicated for infections caused by susceptible organisms in-
Upper respiratory tract infections including sinusitis, pharyngitis and tonsillitis
Lower respiratory tract infections including bronchitis, acute bacterial exacerbations of chronic obstructive pulmonary
disease (COPD)
Otitis media
Skin and soft tissue infections including cellulitis, pyoderma, erysipelas, wound infections
In diarrhea, Shigellosis
Sexually transmitted diseases, especially in the treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
Genital ulcer disease in men due to Haemophilus ducreyi (chancroid)
Mild or moderate typhoid due to multiple-antibacterial resistant organisms
Prophylaxis against a-hemolytic (viridans group) streptococcal bacterial endocarditis
Other infections including odontogenic infections, bartonella infections, toxoplasmosis, babesiosis

Contraindications
Azithromycin is contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic. Co-administration of ergot derivative and Azithromycin is contraindicated. Azithromycin is contraindicated in patients with hepatic diseases.

Dosage And Administration
Azithromycin tablet can be taken with or without food. Azithromycin suspension should be taken at least 1 hour before or 2 hours after meal.
Oral
Adult
For respiratory tract infections, otitis media and skin & soft tissue infections: 500 mg once daily for 3 days or an alternative to this as 500 mg once on day 1, followed by 250 mg once daily for next 4 days. For sexually transmitted diseases like genital ulcer, non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis : a single 1 gm (1000 mg) dose. For the treatment of urethritis and cervicitis due to Neisseria gonorrhoeae : a single 2 gm (2000 mg) dose. In typhoid, 500 mg once daily for 7 days. In Cholera, a single 1 gm (1000 mg) dose. In Shigellosis, 500 mg once on day 1, followed by 250 mg once daily for next 4 days.
Children:

Age/body weight Daily dose Measuring dropper/spoon Duration
Over 6 months 10 mg/kg According to Physician's 3 days
Recommendation
15-25 kg 200 mg 1 spoonful 3 days
26-35 kg 300 mg 1.5 spoonful 3 days
36-45 kg 400 mg 2 spoonful 3 days

Elderly: same as for adults

Injection
Adults
Community-acquired pneumonia: 500 mg as a single daily dose by the intravenous route for at least two days. Intravenous therapy should be followed by Azithromycin by the oral route at a single, daily dose of 500 mg tablet to complete a 7- to 10-day course of therapy.
Pelvic inflammatory disease: 500 mg as a single daily dose by the intravenous route for one or two days. Intravenous therapy should be followed by Azithromycin by the oral route at a single, daily dose of 250 mg to complete a 7-day course of therapy.
Children
Use and dose must be determied by doctor. Although not currently approved by the FDA, the IV preparation has been studied in children using a dose of 10 mg/kg administered over 1 hour once daily.

Azithromycin injection should be followed by Azithromycin by the oral route as required. The timing of the switch to oral therapy should be done at the discretion of the physician and in accordance with clinical response.


Precautions
As with any antibiotic, observation for signs of super infection with non-susceptable organisms, including fungi, is recommended. Precaution should be taken in patients with more severe renal impairment.

Side Effects
Azithromycin is well tolerated with a low incidence of side-efects. The side-effects include nausea, vomiting, abdominal discomfort (pain/cramps), flatulence, diarrhea, headache, dizziness, and skin rashes and are reversible upon discontinuation of therapy. Reversible elevations in liver transaminases have been observed occasionally. Transient mild reductions in neutrophil counts have occasionally been observed in clinical trials, although causal relationship to Azithromycin has not been established.

Use in pregnancy & lactation
Pregnancy: US FDA pregnancy category B. In the animal studies, no evidence of harm to the fetus due to Azithromycin was found. Because animal reproduction studies are not always predictive of human response, Azithromycin should be used during pregnancy only if clearly needed.
Lactation: It is not known whether Azithromycin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Azithromycin is administered to nursing mother.

Overdosage
There are no data available on overdose with Azithromycin. Typical symptoms of overdosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhoea. Gastric lavage and general supportive measures are indicated.

Commercial Pack
Azithromycin Tablet: Each box contains 2 blister strip of 3 tablets.
Azithromycin 250 Tablet: Each box contains 2 blister strip of 3 tablets.
Azithromycin Dry suspension: Bottle containing dry powder for 20 ml suspension.
Azithromycin 35 ml suspension: Bottle containing dry powder for 35 ml suspension.
Azithromycin injection: Each Pack contains 1 vial of lyophilized powder of Azithromycin USP 500 mg, 1 ampoule of 5 ml water for injection BP for dilution and a 5 ml disposable syringe and a butterfly needle.

buy abortion pills online

on line abortion pill cytotec abortion abortion pills online

abortion pill online purchase

where can i get the abortion pill online online purchase abortion pill abortion pills

buy abortion pills online

cytotec abortion pill buy online abortion pill buy abortion pill online

buy viagra in great britain

viagra erection photos female herbal viagra mail order viagra without prescription

female uk kamagra

non prescription kamagra female herbal kamagra buy kamagra uk

side effects of kamagra jelly

cheapest uk supplier kamagra jelly http://www.cengage.co.in/content/copyright-notice non prescription kamagra jelly

cialis vs amoxil

amoxil uk alternative to amoxicillin amoxicillin for sale

buy thyroxine las vegas

get discount thyroxine online synthroid where to buy thyroxine online

get laxative

buy cheap laxative bisacodyl equivalent buy bisacodyl online

principen online

get ampicillin http://www.cengage.co.in/content/competitive-examinations get principen

abortion pills

buy abortion pill order abortion pill where can i get the abortion pill online

purchasing biaxin

order clarithromycin 250mg http://www3.umu.se/kultmed/kurswebb/default.aspx?id=29 buy cheap biaxin

how to use cipro

cipro dosage female herbal ciprofloxacin generic cipro

clindamycin uk

get discount clindamycin online clindamycin for sale buy cleocin online a href

where to buy dexamethasone online

dexamethasone for sale dexamethasone buy dexone in great britain

buy cheap duricef online uk

duricef for sale Cefadroxil prescription buy where to buy duricef online

natural vantin alternatives

vantin uk buy cheap cefpodoxime online uk buy vantin online

buy ceftin las vegas

purchase ceftin online cefuroxime how to use cefuroxime

abortion pills

where can i buy abortion pills abortion pill cytotec abortion pill buy online

buy keflex online safe

buy cephalexin on the internet keflex online uk get discount cephalexin online

chloromycetin without prescription

purchase chloramphenicol online http://www.fareastjournals.com/conf_detail.aspx?conf_id=6 generic chloromycetin online

buy the abortion pill online

where can i buy abortion pills abortion pill pill for abortion online

get clavulanate

mail order augmentin augmentin how to use clavulanate
infidelity my girl friend cheated on me why do wife cheat on husband
cheater why do guys cheat why do people cheat
where can i get an abortion go coat hanger abortion

SkinVD.com | Terms of Use
Home | About Us | My Career | Picture Gallery | Contact Us